GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine. The copper complex and metal-free GHK are related but analytically distinct materials.

Research context

Cell and tissue studies have examined GHK-Cu in relation to fibroblast behavior, collagen synthesis, and matrix-metalloproteinase regulation. These findings are experimental and should not be generalized into universal tissue-regeneration, antioxidant, cosmetic, or therapeutic claims.

Common analytical research areas

• Copper-peptide coordination and complex stability.
• Fibroblast and extracellular-matrix signaling in cell models.
• Comparison of copper-bound GHK with metal-free GHK.

Selected scientific references

• GHK-Cu and collagen synthesis in fibroblasts (PMID 3169264)
• GHK-Cu and matrix metalloproteinase expression (PMID 11045606)

Research-use notice: Supplied exclusively for laboratory research and analytical use. Not for human or veterinary use, diagnosis, treatment, food, cosmetic, or household use.

Specification record updated 28 Sept 2026. External database links are provided for research context; verify primary sources before analytical use.